Association of Leukocyte Telomere Length with Fatigue in Nondisabled Older Adults
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منابع مشابه
Association of Leukocyte Telomere Length with Fatigue in Nondisabled Older Adults
Introduction. Fatigue is often present in older adults with no identified underlying cause. The accruing burden of oxidative stress and inflammation might be underlying factors of fatigue. We therefore hypothesized that leukocyte telomere length (LTL) is relatively short in older adults who experience fatigue. Materials and Methods. We assessed 439 older nondisabled Danish twins. LTL was measur...
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STUDY OBJECTIVES Insomnia, particularly in later life, may raise the risk for chronic diseases of aging and mortality through its effect on cellular aging. The current study examines the effects of insomnia on telomere length, a measure of cellular aging, and tests whether insomnia interacts with chronological age to increase cellular aging. METHODS A total of 126 males and females (60-88 y) ...
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Background Previous studies on physical activity and telomere length have relied largely upon self-reported physical activity data, and few studies have examined older adults. The association of objectively measured physical activity with leukocyte telomere length (LTL) is currently unknown. Methods In this study, we examined cross-sectional associations between accelerometer-measured total, ...
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In culture, replicating human somatic cells display progressive telomere shortening. Ultimately, such cells either undergo apoptosis or enter a state of replicative senescence that is triggered by critically shortened telomeres. Accordingly, telomere length is an index of both the replicative history and the replicative potential of human somatic cells in culture (1). Most replicating human som...
متن کاملLeukocyte telomere length and marital status among middle-aged adults.
BACKGROUND being unmarried is associated with worse health and increased mortality risk. Telomere length has emerged as a marker for biological ageing but it is unclear how telomere length relates to marital status. OBJECTIVE to examine the relationship between telomere length and marital status in a sample of middle-aged adults. DESIGN AND SUBJECTS cross-sectional analysis among 321 adults...
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ژورنال
عنوان ژورنال: Journal of Aging Research
سال: 2014
ISSN: 2090-2204,2090-2212
DOI: 10.1155/2014/403253